Practice Question
Which of the following medications work by preventing the breakdown of acetylcholine, increasing its availability in the brain and helping to improve client symptoms?
Answer Choices:
Correct Answer:
Donepezil
Rationale:
🔷 Donepezil is a cholinesterase inhibitor prescribed primarily for Alzheimer’s disease. It works by blocking the enzyme acetylcholinesterase, which normally breaks down acetylcholine. By inhibiting this breakdown, donepezil increases the availability of acetylcholine in the brain, supporting memory, learning, and cognitive functioning.
🔷 This helps to improve symptoms and slow progression in the early to moderate stages of Alzheimer’s, although it does not cure the disease.
🔷 The other medications listed do not work this way:
Diazepam → benzodiazepine used for anxiety, seizures, muscle spasms.
Diphenhydramine → antihistamine for allergies, causes sedation.
Dexamethasone → corticosteroid used to reduce inflammation.
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This question is from PN pharmacology Final September 18 2025 which contains 85 questions.
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Question Details
- Category: LPN Nursing Exam(s)
- Subcategory: LPN ATI Exams
- Domain: Pharmacology
- Answer Choices: 4