Practice Question
The nurse is preparing to administer ibuprofen to a client. To minimize the risk of gastric distress and bleeding, how should the nurse administer this medication?
Answer Choices:
Correct Answer:
Administer the ibuprofen on an empty stomach to enhance absorption
Rationale:
🔷 Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can cause gastric irritation, ulceration, and bleeding by inhibiting prostaglandin synthesis, which normally protects the stomach lining.
🔷 To reduce this risk, it should be taken with meals, milk, or a snack, which helps buffer the stomach and prevent gastric upset.
🔷 Administering ibuprofen on an empty stomach may improve absorption slightly but significantly increases risk of gastric distress.
🔷 Crushing tablets is unnecessary unless prescribed in liquid form, and ibuprofen is absorbed primarily in the small intestine, not the large intestine.
🔷 Sitting upright after administration is important for some medications (e.g., bisphosphonates like alendronate) to prevent esophageal irritation, but it is not required for ibuprofen.
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This question is from PN pharmacology Final September 18 2025 which contains 85 questions.
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Question Details
- Category: LPN Nursing Exam(s)
- Subcategory: LPN ATI Exams
- Domain: Pharmacology
- Answer Choices: 4