Practice Question
What type of anemia is caused by lack of intrinsic factor?
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Correct Answer:
Pernicious anemia
Rationale:
💎 Pernicious anemia is a type of vitamin B₁₂ deficiency anemia that occurs when the body lacks intrinsic factor, a glycoprotein secreted by the gastric parietal cells.
💎 Without intrinsic factor, vitamin B₁₂ cannot be absorbed in the ileum, leading to impaired red blood cell (RBC) production and resulting in megaloblastic anemia.
💎 Symptoms include fatigue, pallor, glossitis (smooth, red tongue), and neurological manifestations such as numbness, tingling, and balance disturbances due to demyelination.
💎 Treatment involves lifelong vitamin B₁₂ replacement, usually through intramuscular injections, since oral supplementation is ineffective without intrinsic factor.
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This question is from Examplify NR283 Quiz 3a BSNOL SEPT25 which contains 19 questions.
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: Examplify Exam(s)
- Domain: Medical-Surgical
- Answer Choices: 4