Practice Question
Which pharmacokinetic process may be altered in older adult clients due to decreased total body water? Answers: A-D
Answer Choices:
Correct Answer:
Distribution
Rationale:
💧 Distribution refers to the movement of a drug throughout the body’s fluids and tissues.
💧 Older adults have decreased total body water and increased body fat, which alters the volume of distribution of hydrophilic and lipophilic drugs.
💧 Hydrophilic drugs (e.g., aminoglycosides) may have higher plasma concentrations, increasing toxicity risk.
💧 Lipophilic drugs (e.g., benzodiazepines) may have a prolonged half-life due to storage in fat tissue.
💧 Understanding altered distribution is crucial for safe dosing in older adults.
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This question is from W2 NR293 Uniform Quiz which contains 18 questions.
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Answer Choices:
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: Examplify Exam(s)
- Domain: 🔱RN Custom~Exams
- Answer Choices: 4