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1 :

Hint : ๐Ÿ’ฆ Total body water affects drug spread

Correct Answers:

  • Distribution


Rationale :

๐Ÿ’ง Distribution refers to the movement of a drug throughout the bodyโ€™s fluids and tissues.

๐Ÿ’ง Older adults have decreased total body water and increased body fat, which alters the volume of distribution of hydrophilic and lipophilic drugs.

๐Ÿ’ง Hydrophilic drugs (e.g., aminoglycosides) may have higher plasma concentrations, increasing toxicity risk.

๐Ÿ’ง Lipophilic drugs (e.g., benzodiazepines) may have a prolonged half-life due to storage in fat tissue.

๐Ÿ’ง Understanding altered distribution is crucial for safe dosing in older adults.


Distractor Analysis :

Rationale for Incorrect Options to be Available Soon

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