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Practice Question

A nurse caring for a patient with progressive cancer notes that the patient has experienced significant loss of skeletal muscle and fat. Which of the following does the nurse document?

Answer Choices:

Correct Answer:

Cachexia

Rationale:

🥄Cancer cachexia is a multifactorial metabolic syndrome characterized by involuntary loss of skeletal muscle (± fat), anorexia, and systemic inflammation.

🥄Tumor-derived factors (e.g., PIF, cytokines TNF-α, IL-1, IL-6) drive proteolysis and lipolysis, increase resting energy expenditure, and blunt anabolic signaling, causing refractory weight loss.

🥄Unlike simple starvation, cachexia features muscle wasting despite adequate intake, and is not fully reversible by conventional nutrition support.

🥄Consequences include impaired function, treatment intolerance, and worse survival, making early multimodal care (nutrition, exercise, anti-inflammatories, appetite stimulants) crucial.

🥄Structured assessment (e.g., weight trajectory, SMI on CT, grip strength) guides interventions and goals of care.

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This question is from ☑️ NR412-EXAM4 which contains 50 questions.

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Question Details
  • Category: RN Nursing Exam(s)
  • Subcategory: Examplify Exam(s)
  • Domain: Pathophysiology
  • Answer Choices: 4
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