Practice Question
A client with a history of anaphylactic reaction to penicillin receives a prescription for cephalexin 500 mg PO twice daily. Which action should the nurse take?
Answer Choices:
Correct Answer:
Contact the healthcare provider.
Rationale:
🔶 Cephalexin, a cephalosporin, has a known potential for cross-reactivity with penicillin in clients with a history of anaphylaxis.
🔶 Even though the cross-allergy rate is low (about 1–4%), a history of anaphylactic reaction to penicillin warrants extreme caution.
🔶 The nurse must prioritize client safety by notifying the provider to consider an alternative antibiotic.
🔶 Administering cephalexin without prior clearance may expose the client to life-threatening allergic responses, including airway compromise and shock.
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This question is from HESI-RN~311 Pharmacology which contains 40 questions.
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: HESI Exam(s)
- Domain: Hesi Pharmacology
- Answer Choices: 4