Practice Question
A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines that the client has been self-administering St. John's Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?
Answer Choices:
Correct Answer:
Wort can decrease plasma concentrations of cyclosporine.
Rationale:
◈ St. John’s Wort is a known CYP3A4 inducer, which can decrease plasma levels of cyclosporine, increasing the risk of organ rejection.
◈ This interaction is especially dangerous in post-transplant clients who depend on stable immunosuppression.
◈ Nurses must assess all herbal supplement use and inform providers of any potential contraindicated interactions.
◈ Educating clients to avoid unverified herbal advice is critical for transplant outcomes.
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This question is from HESI-RN Pharmacology Exam 2 which contains 36 questions.
More Questions from This Exam
The nurse is administering the muscle relaxant baclofen by mouth (PO) to a client diagnosed with multiple sclerosis. Which intervention should the nurse implement?
Answer Choices:
A. Advise the client to move slowly and cautiously when rising and walking.
B. Monitor intake and output every 8 hours.
C. Ensure the client knows to stop baclofen before using other antispasmodics.
D. Evaluate muscle strength every 4 hours.
A female client who is a vegetarian has a new prescription for warfarin. The client states she eats leafy green vegetables every day. How should the nurse respond?
Answer Choices:
A. Suggest that the client replace the leafy vegetables with a protein source such as nuts or beans.
B. Advise the client that the healthcare provider needs to be made aware of her current diet
C. Commend the client for her healthy lifestyle and encourage her to continue her current diet habits.
D. Confirm that her diet choices will help the medication be more effective in preventing blood clots.
A client in the surgical recovery area asks the nurse to bring the largest possible dose of pain medication available. Which action should the nurse implement first?
Answer Choices:
A. Ask the client to rate the current level of pain using a pain scale.
B. Encourage the client to use diversional thoughts to manage pain.
C. Review the history for a past use of recreational drugs.
D. Determine when the last dose was administered.
The nurse is planning care for a client with major depression who is receiving a new prescription for duloxetine. Which information is most important for the nurse to obtain?
Answer Choices:
A. Family history of mental illness
B. Weight change in the last month.
C. Liver function laboratory results.
D. Recent use of other antidepressants.
Prior to administering oral doses of calcitriol and calcium carbonate to a client with hypoparathyroidism, the nurse notes that the client's total calcium level is 14 mg/dL (3.5 mmol/L). Which action should the nurse implement? Reference Range: Total Calcium - Reference Range: Adult 9 to 10.5 mg/dL or 2.25 to 2.62 mmol/L
Answer Choices:
A. Administer both prescribed medications as scheduled.
B. Hold both medications until contacting the healthcare provider.
C. Hold the calcium carbonate, but administer the calcitriol as scheduled
D. Hold the, calcitriol but administer the calcium carbonate as scheduled.
Question Details
- Category: RN Nursing Exam(s)
- Subcategory: HESI Exam(s)
- Domain: Hesi Pharmacology
- Answer Choices: 4
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