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HESI-RN Pharmacology Exam 2

RN Nursing Exam(s) 36 Questions 🔒 Premium Content

This exam evaluates the nursing student’s understanding of pharmacological principles, including drug classifications, mechanisms of action, side effects, contraindications, and safe medication administration practices essential for safe and effective client care.

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Sample Questions with Detailed Explanations

Below are sample questions from this exam.

Q1: The nurse is administering the muscle relaxant baclofen by mouth (PO) to a client diagnosed with multiple sclerosis. Which intervention should the nurse implement?

A. Advise the client to move slowly and cautiously when rising and walking.
B. Monitor intake and output every 8 hours.
C. Ensure the client knows to stop baclofen before using other antispasmodics.
D. Evaluate muscle strength every 4 hours.
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Q2: A female client who is a vegetarian has a new prescription for warfarin. The client states she eats leafy green vegetables every day. How should the nurse respond?

A. Suggest that the client replace the leafy vegetables with a protein source such as nuts or beans.
B. Advise the client that the healthcare provider needs to be made aware of her current diet
C. Commend the client for her healthy lifestyle and encourage her to continue her current diet habits.
D. Confirm that her diet choices will help the medication be more effective in preventing blood clots.
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Q4: A client in the surgical recovery area asks the nurse to bring the largest possible dose of pain medication available. Which action should the nurse implement first?

A. Ask the client to rate the current level of pain using a pain scale.
B. Encourage the client to use diversional thoughts to manage pain.
C. Review the history for a past use of recreational drugs.
D. Determine when the last dose was administered.
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Q5: The nurse is planning care for a client with major depression who is receiving a new prescription for duloxetine. Which information is most important for the nurse to obtain?

A. Family history of mental illness
B. Weight change in the last month.
C. Liver function laboratory results.
D. Recent use of other antidepressants.
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Access All 36 Questions with Full Explanations

Exam Details
Total Questions: 36 practice questions
Category: RN Nursing Exam(s)
Subcategory: HESI Exam(s)
Domain: Hesi Pharmacology
Last Updated: Dec 09, 2025
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