Practice Question
A patient with chronic arthritis pain reports taking acetaminophen 4 to 6 g/day for arthritis pain. Which health problem should you teach this patient that can occur as a result of taking this acetaminophen therapy?
Answer Choices:
Correct Answer:
"Liver toxicity can result as a result of high acetaminophen doses."
Rationale:
⚠️Acetaminophen at doses >4 g/day (and sometimes even lower in at-risk patients) can cause hepatic injury due to accumulation of the toxic metabolite NAPQI.
⚠️Chronic high intake increases risk of acute liver failure, especially with alcohol use, malnutrition, or underlying liver disease.
⚠️Educate that the maximum daily dose from all sources (including combination cold/analgesic products) should generally not exceed 3–4 g.
⚠️Early signs of toxicity can be nausea, vomiting, right upper quadrant pain, and elevated liver enzymes; severe cases progress to coagulopathy and encephalopathy.
⚠️Safer pain plans may include dose reduction, scheduled dosing within limits, or alternative agents under provider guidance.
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This question is from Custom FRIEDMAN-PHARM-CH 12-13-15 (Pain-Inflam-Immune) (1) which contains 52 questions.
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From Exam
Custom FRIEDMAN-PHARM-CH 12-13-15 (Pain-Inflam-Immune) (1)
52 Questions
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- Category: LPN Nursing Exam(s)
- Subcategory: LPN ATI Exams
- Domain: Pharmacology
- Answer Choices: 4