Practice Question
A nurse is assisting in explaining the pathophysiology of systemic inflammatory response syndrome (SIRS) to a group of newly licensed nurses. Which of the following statements by the nurse is accurate?
Answer Choices:
Correct Answer:
“A deregulated cytokine storm causes an inflammatory response."
Rationale:
♦️SIRS arises from a dysregulated host response in which pro-inflammatory cytokines (e.g., TNF-α, IL-1, IL-6) surge and amplify systemic inflammation.
♦️This cytokine storm injures the endothelium, increases capillary permeability, and triggers vasodilation, leading to maldistribution of blood flow.
♦️The result is tissue hypoperfusion and a cascade that may evolve to multiple organ dysfunction.
♦️Coagulation pathways are also activated, promoting microthrombi and worsening organ ischemia.
♦️Recognizing the cytokine-driven pathophysiology explains why early source control, hemodynamic support, and anti-inflammatory/antimicrobial strategies are central to care.
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This question is from Custom Adult Hlth I Cardiovascular Test 2 which contains 59 questions.
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Question Details
- Category: LPN Nursing Exam(s)
- Subcategory: LPN ATI Exams
- Domain: Adult Health
- Answer Choices: 4