Practice Question
Which of the following is a second-generation nonsteroidal anti-inflammatory drug (NSAID)?
Answer Choices:
Correct Answer:
Celecoxib.
Rationale:
♦️ Celecoxib is classified as a second-generation NSAID, specifically a selective COX-2 inhibitor.
♦️ It selectively inhibits COX-2 enzyme responsible for pain and inflammation, significantly reducing the risk of gastrointestinal side effects associated with traditional NSAIDs.
♦️ Unlike first-generation NSAIDs (e.g., ibuprofen, aspirin), celecoxib does not inhibit COX-1, reducing the likelihood of gastric ulcers and bleeding.
♦️ Clinically, celecoxib is used to manage arthritis, acute pain, and dysmenorrhea, offering effective pain relief with improved gastrointestinal tolerability.
♦️ Nurses should educate patients to take celecoxib with food if stomach upset occurs and to report any cardiovascular symptoms, as COX-2 inhibitors carry a potential increased cardiovascular risk.
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This question is from Custom 3 -PNSG 1600 EXAM 2-2025 (Summer) which contains 44 questions.
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Question Details
- Category: LPN Nursing Exam(s)
- Subcategory: LPN ATI Exams
- Domain: Pharmacology
- Answer Choices: 4