QLexNursing

Sublimaze (Fentanyl)

🟠Fentanyl (Sublimaze) is a potent synthetic opioid agonist commonly used for pain management, especially for severe pain and anesthesia.

🟠It binds strongly to opioid receptors in the central nervous system, providing profound analgesia.

🟠Clinicians must monitor for respiratory depression due to its potency.

Morphine

🟠Morphine is a well-known natural opioid agonist frequently utilized in clinical settings to relieve moderate to severe pain.

🟠It activates mu opioid receptors in the central nervous system, altering the perception and response to pain.

🟠Monitoring for adverse effects such as respiratory depression, sedation, constipation, and addiction potential is critical.

Fentanyl

🟠Fentanyl is specifically highlighted again for its strong analgesic properties and high affinity for opioid receptors.

🟠Due to its rapid onset and short duration, fentanyl is extensively used in anesthesia, pain management, and procedural sedation.

🟠Close monitoring is essential because of its high risk for respiratory depression, sedation, and potential for abuse.

Dolophine (Methadone)

🟠Dolophine (Methadone) is a synthetic opioid agonist commonly used in chronic pain management and opioid addiction treatment programs.

🟠Methadone has a prolonged half-life, offering sustained pain relief and reducing withdrawal symptoms in opioid-dependent clients.

🟠Regular cardiac monitoring is recommended due to the risk of QT prolongation associated with methadone.

Demerol (Meperidine)

🟠Demerol (Meperidine) is a synthetic opioid agonist indicated for moderate to severe acute pain management, including perioperative use.

🟠Meperidine acts primarily by stimulating opioid receptors to produce analgesia and sedation.

🟠Caution is advised due to the risk of CNS excitability, seizures (especially with prolonged use), and respiratory depression.