Practice Question
A nurse is providing teaching to a client who has rheumatoid arthritis and a new prescription for methotrexate. Which of the following instructions should the nurse include? (Select all that apply.)
Answer Choices:
Correct Answer:
Avoid people who have infections.
Rationale:
💠Avoid people who have infections
💠 Methotrexate is an immunosuppressant and antimetabolite that decreases inflammation by suppressing the immune response.
💠 Because it lowers bone marrow activity, the client becomes more susceptible to infections. Even minor infections can progress rapidly in immunocompromised patients.
💠 The nurse should instruct the client to avoid crowded areas, people who are ill, and to report any fever, sore throat, or signs of infection promptly.
💠 This precaution helps prevent serious complications such as pneumonia or sepsis in immunosuppressed individuals.
💠Do not drink alcoholic beverages while taking this medication
💠 Methotrexate is hepatotoxic, meaning it can cause liver damage.
💠 Consuming alcohol while taking methotrexate significantly increases the risk of liver toxicity and potential hepatic failure.
💠 Clients should be taught to completely avoid alcohol and to report signs of liver injury such as jaundice, dark urine, or fatigue.
💠 Regular liver function tests (LFTs) should be done to monitor for hepatic damage during therapy.
💠Report unexplained bruising to the provider
💠 Unexplained bruising, petechiae, or bleeding may indicate bone marrow suppression, a serious adverse effect of methotrexate.
💠 This suppression can lead to thrombocytopenia (low platelets) or leukopenia, increasing the risk of bleeding and infection.
💠 The nurse should educate the client to report these symptoms immediately so that the provider can adjust the dose or discontinue the medication.
💠 Frequent CBC monitoring is essential to detect early signs of hematologic toxicity.
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This question is from Custom-2201 Unit 2 -Heme-Endocrine-Autoimmune- Fall 2025 which contains 53 questions.
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From Exam
Custom-2201 Unit 2 -Heme-Endocrine-Autoimmune- Fall 2025
53 Questions
View Full Exam Start PracticingQuestion Details
- Category: RN Nursing Exam(s)
- Subcategory: ATI Exam(s)
- Domain: RN ATI MedSurg
- Answer Choices: 5