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Practice Question

The nurse instructs a patient taking which antibiotic(s) to wear sunscreen and a hat and to avoid the sun between 10 AM and 4 PM? (Select all that apply.)

Answer Choices:

Correct Answer:

Cotrimoxazole (Bactrim)

Rationale:

🌞 Cotrimoxazole (Bactrim)

♦️Belongs to the sulfonamide class of antibiotics, which are well-known to cause photosensitivity reactions.

♦️Patients may experience severe sunburns, rashes, or blistering even with limited sun exposure.

♦️The mechanism involves drug-induced skin hypersensitivity to ultraviolet (UV) radiation, leading to DNA damage and exaggerated inflammatory response.

♦️Nurses should educate patients to:

💥Apply broad-spectrum sunscreen (SPF 30 or higher) before going outdoors.

💥Wear protective clothing such as long sleeves and wide-brimmed hats.

💥Avoid sun exposure between 10 AM and 4 PM, when UV radiation is strongest.

♦️This teaching is critical because Bactrim is commonly prescribed for urinary tract infections, skin infections, and Pneumocystis pneumonia, conditions often requiring extended courses of therapy.

🌞 Demeclocycline (Declomycin)

♦️A member of the tetracycline antibiotic family, which is also strongly associated with photosensitivity.

♦️Photosensitivity may present as redness, itching, rash, or blistering after sun exposure. In severe cases, long-term skin damage can occur.

♦️The drug works by inhibiting bacterial protein synthesis but inadvertently makes the skin more reactive to UV light.

♦️Nurses should emphasize the same sun safety precautions as with Bactrim: sunscreen, protective clothing, and limiting peak-time exposure.

♦️Beyond photosensitivity, tetracyclines like demeclocycline should not be taken with milk or antacids, as calcium and magnesium reduce absorption.

♦️Since demeclocycline is sometimes used long-term (e.g., for SIADH management), repeated sun exposure risk becomes a real concern if precautions are not followed.

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Question Details
  • Category: RN Nursing Exam(s)
  • Subcategory: ATI Exam(s)
  • Domain: RN ATI Pharmacology
  • Answer Choices: 6
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