Practice Question
A nurse is caring for a client who has diabetes mellitus and is taking pioglitazone. The nurse should plan to monitor the client for which of the following adverse effects?
Answer Choices:
Correct Answer:
Fluid retention
Rationale:
🟦 Pioglitazone is a thiazolidinedione that improves insulin sensitivity but commonly causes fluid retention due to renal sodium reabsorption changes.
🟦 This effect can lead to weight gain and peripheral edema, especially in clients with underlying cardiac risk.
🟦 Fluid retention may worsen or precipitate heart failure, making monitoring for swelling, shortness of breath, and rapid weight changes essential.
🟦 Early detection allows providers to adjust therapy to prevent serious cardiopulmonary complications.
🟦 Monitoring for edema and sudden weight gain is a key nursing priority with pioglitazone therapy.
❌ Tinnitus
🟦 Tinnitus is more commonly associated with salicylates or ototoxic medications.
🟦 Pioglitazone does not typically affect auditory function.
❌ Orthostatic hypotension
🟦 Orthostatic hypotension is more associated with antihypertensives or dehydration.
🟦 It is not a primary adverse effect of pioglitazone.
❌ Insomnia
🟦 Insomnia is not a common adverse reaction with this medication class.
🟦 Pioglitazone primarily affects glucose metabolism and fluid balance.
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This question is from RN Pharmacology 2023 Dec 17 which contains 70 questions.
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: ATI Exam(s)
- Domain: RN ATI Pharmacology
- Answer Choices: 4