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RN Medical Surgical Exam 2025

RN Nursing Exam(s) 55 Questions 🔒 Premium Content

This is a custom RN HESI Medical-Surgical practice exam. It tests your clinical judgment, prioritization, and knowledge of adult medical-surgical conditions, nursing interventions, and patient safety in alignment with the HESI exam style.

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55 Questions
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Sample Questions with Detailed Explanations

Below are sample questions from this exam.

Q1:  Which assessment finding should the nurse expect in a client with fluid volume excess?

A. Flushed skin.
B. Elevated blood pressure.
C. Weak, thready pulse.
D. Dry mucous membranes.
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Q2: A client is using an otic solution, hydrocortisone, neomycin, and polymyxin B for external otitis media. Which therapeutic response should the nurse tell the client to expect?

A. Slows the rate of organism growth
B. Decreases inflammation and pain
C. Reduces the existing colony count
D. Prevents hearing loss as a possible complication.
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Q3:  A female client with rheumatoid arthritis takes ibuprofen 600 mg PO 4 times a day. To prevent gastrointestinal bleeding, misoprostol 100 mcg PO is prescribed. Which information is most important for the nurse to include in client teaching?

A. Use contraception during intercourse
B. Ensure the Cytotec is taken on an empty stomach
C. Take Cytotec 30 minutes prior to Motrin
D. Encourage oral fluid intake to prevent constipation.
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Q4:  A client is admitted to the hospital with a medical diagnosis of pneumococcal pneumonia. The nurse knows that the prognosis for gram-negative pneumonias (such as E. coli, Klebsiella, Pseudomonas, and Proteus) is very poor. Which information relates most directly to the prognosis for gram-negative pneumonias?

A. Gram-negative organisms are more resistant to antibiotic therapy
B. Usually occur in healthy young adults who have recently been debilitated by an upper respiratory infection.
C. The gram-negative infections occur in the lower lobe alveoli which are more sensitive to infection.
D. Gram-negative pneumonias usually affect infants and small children.
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Exam Details
Total Questions: 55 practice questions
Category: RN Nursing Exam(s)
Subcategory: HESI Exam(s)
Domain: Hesi MedSurg
Last Updated: Dec 09, 2025
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