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RN-HESI Pharmacology Exam 3

RN Nursing Exam(s) 40 Questions 🔒 Premium Content

This exam evaluates the nursing student’s understanding of pharmacological principles, including drug classifications, mechanisms of action, side effects, contraindications, and safe medication administration practices essential for safe and effective client care.

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Below are sample questions from this exam.

Q1: A client with anemia secondary to chronic kidney disease (CKD) started a prescription for epoetin alfa two months ago. Which client finding best indicates that the medication is effective? Reference Range: Hemoglobin (Hgb) [14 to 18 g/dL (8.7 to 11.2 mmol/L)].

A. Takes concurrent iron therapy without adverse effects.
B. Reports of increased energy levels and decreased fatigue.
C. Hemoglobin level increased to 12 g/dl. (7.45 mmol/L).
D. Food diary shows increased consumption of iron-rich foods.
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Q2: To control asthma, a client in a residential treatment facility uses a fluticasone propionate and salmeterol discus inhalation system, which provides an inhaled powdered form of these combined medications. Which instruction should the nurse provide to this client's caregivers?

A. When using the discus, have the client breathe out rapidly into the mouthpiece
B. Offer the discus to the client for use during an acute asthma attack.
C. Clients using the discus may experience decreased blood pressure.
D. Explain that the client should not use the discus more than twice daily.
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Q4: The nurse is caring for a client receiving a prescription for sucralfate to treat a peptic ulcer. Which instruction should the nurse provide during discharge education?

A. Continue with normal dose schedule after missing a dose.
B. Administer an additional dose if a dose is missed.
C. Take on an empty stomach at least 1 hour before meals.
D. Schedule doses with each meal and at bedtime.
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Q5: A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines that the client has been self-administering St. John's Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?

A. Adding the herb can decrease the need for corticosteroids.
B. The client probably used this herb to treat depression.
C. Ingestion of St. John's Wort can reduce the client's intake of sodium.
D. St. John's Wort can decrease plasma concentrations of cyclosporine.
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Exam Details
Total Questions: 40 practice questions
Category: RN Nursing Exam(s)
Subcategory: HESI Exam(s)
Domain: Hesi Pharmacology
Last Updated: Dec 09, 2025
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