Practice Question
Which of the following may cause peptic ulcer disease?
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Correct Answer:
Helicobacter pylori infection
Rationale:
💎 H. pylori colonizes the gastric mucosa and produces urease, generating ammonia that alkalinizes the microenvironment and disrupts mucosal defenses.
💎The organism triggers chronic inflammation (gastritis) and increases gastrin release, promoting acid secretion that contributes to gastric and duodenal ulcers.
💎Eradication of H. pylori (e.g., PPI + two antibiotics) significantly reduces ulcer recurrence, underscoring its causal role in peptic ulcer disease.
💎Diagnostic tests such as the urea breath test, stool antigen, or biopsy-based methods confirm active infection.
💎Recognizing H. pylori as a major etiology guides targeted therapy and long-term prevention of ulcer complications like bleeding and perforation.
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This question is from Patho FINAL NSG1520 Summer 2025 PGH SJC which contains 105 questions.
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Question Details
- Category: LPN Nursing Exam(s)
- Subcategory: 💎Examplify-PN
- Domain: 👩🏼🔬Pathophysiology-PN
- Answer Choices: 4