Practice Question
A client receives a new prescription for zafirlukast. Prior to administering the medication, the nurse should review the electronic medical record for which condition?
Answer Choices:
Correct Answer:
Cholecystitis.
Rationale:
🟦 Zafirlukast is associated with hepatic dysfunction, so any history of liver or biliary disease such as cholecystitis requires careful review.
🟦 Clients with cholecystitis may have impaired bile flow, which affects drug metabolism and increases risk for elevated liver enzymes.
🟦 Zafirlukast has been linked to cases of hepatic injury, requiring monitoring of LFTs if liver-related conditions exist.
🟦 Reviewing this history helps prevent complications such as jaundice, abdominal pain, or liver inflammation.
🟦 This assessment supports safe administration and early identification of adverse hepatic reactions.
Obesity
🟦 Obesity does not interfere with zafirlukast’s metabolism or required precautions.
🟦 Not considered a contraindication or high-risk condition for this medication.
Diabetes mellitus
🟦 Zafirlukast does not significantly affect blood glucose levels.
🟦 No major interactions occur with typical diabetes medications.
Cerebrovascular accident
🟦 Prior stroke does not alter how the medication is processed or tolerated.
🟦 Not identified as a condition requiring special precautions with zafirlukast.
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This question is from HESI EXIT 2025 Exam.. which contains 126 questions.
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: HESI-Exit Exam(s)
- Domain: HESI Exit Exam(s)~2025
- Answer Choices: 4