Practice Question
The nurse is in an interdisciplinary team meeting discussing possible treatments for a client who requires anticoagulation therapy. What should the nurse understand about the advantage of using rivaroxaban versus warfarin in clients requiring anticoagulation therapy? (Select all that apply) .
Answer Choices:
Correct Answer:
Rivaroxaban does not require INR monitoring
Rationale:
Rivaroxaban does not require INR monitoring
🟪 Rivaroxaban is a direct factor Xa inhibitor, which has predictable pharmacokinetics and does not require routine INR monitoring like warfarin.
🟪 This simplifies management for patients and healthcare providers, reducing the burden of frequent lab visits.
🟪 INR monitoring is essential for warfarin because of its narrow therapeutic window and multiple food-drug and drug-drug interactions.
🟪 By contrast, rivaroxaban maintains consistent anticoagulation levels, allowing for fixed dosing.
🟪 This is a major advantage in improving adherence and convenience for long-term anticoagulation therapy.
The anticoagulant effect clears in 1–2 days after discontinuation
🟪 Rivaroxaban has a short half-life, typically between 5 to 13 hours, depending on age and renal function.
🟪 Because of this, its anticoagulant effect diminishes within 1 to 2 days of stopping the medication.
🟪 This feature is particularly beneficial in situations requiring urgent surgery or procedures that pose a bleeding risk.
🟪 In contrast, warfarin can take up to 5 days or more to clear due to its longer half-life and effect on vitamin K–dependent clotting factors.
🟪 A shorter clearance time improves clinical flexibility and reduces risks during medication transitions or emergencies.
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This question is from Exam 3 - Modules 5 and 6 which contains 73 questions.
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: General Exams
- Domain: 🚑Pharmacology
- Answer Choices: 5