Practice Question
A 65-year-old patient with a history of pernicious anemia presents with fatigue, numbness and tingling in the hands and feet, and a recent blood test revealing macrocytic anemia. Which vitamin deficiency should the nurse prioritize in the care plan to address the patient's condition?
Answer Choices:
Correct Answer:
Vitamin B12 deficiency
Rationale:
🔷 Pernicious anemia results from a lack of intrinsic factor, which is necessary for vitamin B12 absorption in the ileum.
🔷 Vitamin B12 deficiency leads to macrocytic (megaloblastic) anemia, characterized by large, immature red blood cells and neurological manifestations such as numbness, tingling, and fatigue.
🔷 Without replacement therapy (usually parenteral B12), irreversible neuropathy and cognitive impairment may occur.
🔷 Long-term management includes lifelong vitamin B12 injections or high-dose oral supplements if absorption improves.
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This question is from Custom RN PN Pharmacology Midterm Fall 2025 which contains 75 questions.
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Question Details
- Category: RN Nursing Exam(s)
- Subcategory: ATI Exam(s)
- Domain: RN ATI Pharmacology
- Answer Choices: 4