Practice Question
Which of the following cell types is responsible for secreting acids to dissolve the bony matrix?
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Correct Answer:
Osteoclasts
Rationale:
🟥Osteoclasts are multinucleated bone-resorbing cells that secrete acids and proteolytic enzymes to dissolve the mineral and organic matrix.
🟥Their ruffled border creates a sealed resorption lacuna where H⁺ is pumped to acidify and decalcify bone.
🟥This process releases calcium and phosphate, contributing to mineral homeostasis.
🟥Bone remodeling depends on the balanced activity of osteoclasts (resorption) and osteoblasts (formation).
🟥Dysregulation of osteoclast function leads to skeletal pathology (e.g., osteoporosis, Paget disease).
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This question is from ☑️ ATI TEAS SCIENCE- 16.09.2025 which contains 49 questions.
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Question Details
- Category: ATI TEAS
- Subcategory: Science Exam(s)
- Domain: Science~2025
- Answer Choices: 4