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Practice Question

A nurse is caring for a client who is taking prednisone for long-term treatment of rheumatoid arthritis. The nurse should monitor the client for which of the following adverse effects of this medication?

Answer Choices:

Correct Answer:

Bone loss

Rationale:

🟧 Long-term prednisone increases risk of osteoporosis by decreasing bone formation and increasing bone resorption.

🟧 It also reduces calcium absorption and alters vitamin D metabolism, worsening bone density over time.

🟧 Clients on chronic steroids have higher fracture risk, especially in the spine, hip, and wrist.

🟧 Monitoring includes assessing fracture risk, encouraging weight-bearing activity as appropriate, and ensuring adequate calcium/vitamin D per provider plan.

🟧 Recognizing bone loss as a key chronic complication helps prevent serious long-term morbidity.

Liver toxicity

🟧 Prednisone is not primarily associated with liver toxicity as a common adverse effect.

🟧 Other medications are more characteristically hepatotoxic than corticosteroids.

Hypoglycemia

🟧 Prednisone more commonly causes hyperglycemia, not hypoglycemia.

🟧 It raises blood glucose by promoting gluconeogenesis and insulin resistance.

Hemolytic anemia

🟧 Hemolytic anemia is not a typical adverse effect of prednisone therapy.

🟧 Steroids are sometimes used to treat immune-mediated hemolysis rather than cause it.

Want to practice more questions like this?

This question is from ☑️ ATI RN Pharmacology 2023 VIII which contains 68 questions.

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Answer Choices:

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Answer Choices:

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From Exam
☑️ ATI RN Pharmacology 2023 VIII

68 Questions

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Question Details
  • Category: RN Nursing Exam(s)
  • Subcategory: ATI Exam(s)
  • Domain: RN ATI Pharmacology
  • Answer Choices: 4
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