Practice Question
Which drug groups do not inhibit clot formation? (SELECT ALL THAT APPLY)
Answer Choices:
Correct Answer:
Antihypertensives
Rationale:
✅ B. Antihypertensives
🫀 Antihypertensive medications are used to manage elevated blood pressure, which is a major risk factor for cardiovascular events such as stroke, myocardial infarction, and heart failure.
🫀 These drugs work by affecting vascular tone, cardiac output, or fluid balance, depending on the class (e.g., beta-blockers, ACE inhibitors, calcium channel blockers, or diuretics).
🫀 Importantly, antihypertensives do not act on the blood clotting mechanisms and do not inhibit coagulation or platelet function.
🫀 Their primary role is to control hemodynamics, not prevent thrombus formation.
✅ C. Antibiotics
🦠 Antibiotics are medications designed to kill or inhibit the growth of bacteria, helping the body eliminate infections.
🦠 They target specific bacterial processes like cell wall synthesis, protein synthesis, or DNA replication, depending on the class (e.g., penicillins, macrolides, fluoroquinolones).
🦠 While some rare antibiotics may have adverse effects on platelets or the liver, they do not have a primary mechanism involving the coagulation pathway.
🦠 Therefore, antibiotics do not inhibit clot formation and are not used to treat or prevent thrombotic disorders.
✅ D. Antipyretics
🌡️ Antipyretics (e.g., acetaminophen, ibuprofen) are medications that help reduce fever by acting on the hypothalamic thermoregulatory center to lower the set-point temperature.
🌡️ Although some antipyretics like NSAIDs have mild antiplatelet effects, their primary function is temperature control, not anticoagulation.
🌡️ Acetaminophen, the most commonly used antipyretic, has no significant impact on platelet function or clotting pathways.
🌡️ Therefore, antipyretics as a group do not serve the function of inhibiting clot formation.
✅ E. Antiemetics
🤢 Antiemetics are used to prevent or control nausea and vomiting, especially in postoperative patients, those undergoing chemotherapy, or those with GI illnesses.
🤢 They work by blocking receptors such as dopamine, serotonin, histamine, or acetylcholine in the GI tract and central nervous system.
🤢 Antiemetics have no action on the clotting cascade, platelets, or fibrin formation and thus do not interfere with coagulation.
🤢 Their therapeutic action is purely to relieve gastrointestinal symptoms, not to influence thrombus risk or hemostasis.
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This question is from ATI LPN Pharmacology Exam III which contains 53 questions.
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Question Details
- Category: LPN Nursing Exam(s)
- Subcategory: LPN ATI Exams
- Domain: Pharmacology
- Answer Choices: 5