1 :

Hint : Grapefruit + statins = dangerous drug buildup.

Correct Answers:

  • Grapefruit juice


Rationale :
Grapefruit juice inhibits the CYP3A4 enzyme, which metabolizes simvastatin. This increases serum drug levels and raises the risk of myopathy or rhabdomyolysis. Clients taking simvastatin must avoid grapefruit and grapefruit-containing products.

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2 :

Hint : HDL = Healthy = good cholesterol.

Correct Answers:

  • cholesterol.
  • contraindicated


Rationale :
HDL (high-density lipoprotein) removes excess cholesterol from tissues and transports it to the liver for excretion. This protective role lowers cardiovascular risk, earning it the term "good" cholesterol. High HDL levels are beneficial.

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3 :

Hint : Statins stop cholesterol synthesis at the liver.

Correct Answers:

  • A statin


Rationale :
HMG-CoA reductase inhibitors, commonly called statins, reduce cholesterol synthesis in the liver. These drugs are the first-line treatment for hyperlipidemia. Examples include simvastatin and atorvastatin.

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4 :

Hint : Beta blockers = block the heart’s stress signals.

Correct Answers:

  • Beta blockers


Rationale :
Beta blockers block beta-adrenergic receptors, slowing heart rate and reducing myocardial oxygen demand. They are proven to reduce mortality after myocardial infarction. They also help control blood pressure and arrhythmias.

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5 :

Hint : Stable = predictable. Unstable = worsening, even at rest.

Correct Answers:

  • "Stable angina is predictable in its frequency, intensity, and duration. Unstable angina is when angina episodes become more frequent or severe, and occur during periods of rest."


Rationale :
Stable angina occurs with exertion and resolves with rest or medication. Unstable angina is unpredictable, more intense, and may occur at rest, signaling a risk for myocardial infarction. This distinction is essential in guiding urgency of care.

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6 :

Hint : Angina = effort- or stress-induced chest pain.

Correct Answers:

  • Chest pain on physical exertion or emotional stress


Rationale :
Angina is chest pain caused by myocardial ischemia, typically triggered by physical exertion or stress. The pain is due to an imbalance between oxygen supply and demand. It usually resolves with rest or nitroglycerin.

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7 :

Hint : 50 mg tablet ÷ 2 = 25 mg dose.

Correct Answers:

  • Half tablet


Rationale :
To deliver a 25 mg dose using a 50 mg tablet, the tablet must be split in half. This approach allows gradual titration to minimize side effects. Accurate tablet splitting ensures proper dosing.

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8 :

Hint : Isosorbide = nitrate = vasodilator for angina.

Correct Answers:

  • Nitrates


Rationale :
Isosorbide is a nitrate used to prevent angina by dilating coronary arteries and reducing preload. It decreases myocardial oxygen demand. It is not used for acute attacks but for long-term angina prevention.

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9 :

Hint : Statins help — diet still matters.

Correct Answers:

  • "l can eat any food I want as long as I take my medications."


Rationale :
Cholesterol-lowering medications must be paired with dietary changes for optimal effect. Unrestricted eating undermines the drug’s purpose and increases cardiovascular risk. Client education should emphasize lifestyle changes alongside medication.

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10 :

Hint : 1 tablet every 5 minutes × 3 max — then call 911.

Correct Answers:

  • "For chest pain, put one tablet under your tongue every 5 minutes; taking no more than a total of three tablets."


Rationale :
Sublingual nitroglycerin should be taken at the onset of chest pain, with one tablet every 5 minutes, up to three doses. If pain persists after three doses, emergency services must be contacted. This protocol helps manage angina and detect MI early.

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Total Questions: 10

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