End
1 :

Hint : Beta-blockers can affect bronchial tone.

Correct Answers:

  • Chronic obstructive pulmonary disease (COPD)


Rationale :

πŸ“— Clients with COPD require careful monitoring when receiving beta-blockers because blockade of betaβ‚‚-adrenergic receptors can cause bronchial smooth-muscle constriction.

πŸ“— Nonselective beta-blockers, such as propranolol, block both beta₁ receptors in the heart and betaβ‚‚ receptors in the lungs, increasing the risk for bronchospasm.

πŸ“— Bronchospasm can worsen wheezing, dyspnea, airflow limitation, and hypoxemia in a client who already has compromised pulmonary function.

πŸ“— Cardioselective beta₁-blockers, such as metoprolol, generally have less effect on the lungs and may be used cautiously when clinically indicated, particularly in stable COPD.

πŸ“— The nurse should monitor respiratory rate, breath sounds, oxygen saturation, dyspnea, and changes in exercise tolerance when beta-blocker therapy is initiated or adjusted.

πŸ“— Beta-blockers also decrease heart rate and blood pressure, while nitrates produce vasodilation and can further decrease blood pressure.

πŸ“— The combination therefore requires monitoring for hypotension, dizziness, bradycardia, and syncope, in addition to respiratory effects related to COPD.

πŸ“— Careful medication selection and monitoring allow the cardiovascular benefits of beta-blockade to be balanced against the potential for worsening respiratory symptoms, particularly with nonselective agents.


Distractor Analysis :

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