End
1 :

Hint : 🧠 “Diuresis mirrors ICP drop.”

Correct Answers:

  • Urine output is increased


Rationale :

💧Mannitol is an osmotic diuretic that raises plasma osmolality, pulling water from edematous brain tissue into the intravascular space; the most direct, measurable effect is a prompt rise in urine output.

💧A brisk diuresis confirms that mannitol reached the renal tubules intact (it is freely filtered, not reabsorbed), demonstrating therapeutic action.

💧Reduced intracranial pressure (ICP) follows fluid shift plus diuresis; while neurologic symptoms may improve, urine output is the earliest and most reliable bedside indicator of efficacy.

💧Monitoring hourly I&O and serum osmolality (goal ≈ 300–320 mOsm/kg) helps maintain effectiveness and avoid overdiuresis.

💧The nurse should also trend neurologic checks and ICP (if monitored), but increased urine output is the clearest confirmation of mannitol’s effect at the kidney.


Distractor Analysis :

Rationale for Incorrect Options to be Available Soon

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