End
1 :

She is 24 years old with a body mass index (BMI) of 16.5. She admits to having used cocaine "several times" during the past year and occasionally drinks alcohol. Her blood pressure is 108/70 mm Hg. The family history is positive for diabetes mellitus and cancer. Her sister recently gave birth to an infant with a neural tube defect (NTD). 


Drag and drop the 3 characteristics that place this patient in a high-risk category.


Answer Options

Hint : 🌸 Think genetics, nutrition, and substance risks.

Correct Answers:

  • Family history
  • BMI
  • Drug and alcohol abuse Age


Rationale :

Family history

♦️NTD in a first-degree relative’s child (your niece/nephew) increases this pregnancy’s risk of neural tube defects compared with baseline, signaling a potential genetic/folate-metabolism susceptibility.

♦️Recommend early folic acid supplementation (at least 400–800 mcg/day; discuss dose with clinician given the strong family history) and first-trimester anatomic screening.

♦️A family history of diabetes mellitus raises the mother’s risk for gestational diabetes. Plan early glucose screening (at the first prenatal visit) and repeat standard screening at 24–28 weeks.

BMI (16.5 — underweight)

♦️Underweight (BMI <18.5) is linked to small-for-gestational-age, low birth weight, and preterm birth due to limited maternal nutrient reserves.

♦️Management includes a nutrition consult, iron/overall micronutrient optimization, and counseling toward the IOM gestational weight-gain goal of 28–40 lb (12.5–18 kg) for underweight patients, with serial fundal height/ultrasound growth checks.

Drug and alcohol abuse

♦️Cocaine causes potent vasoconstriction, elevating risks of placental abruption, fetal growth restriction, preterm labor, and fetal demise.

♦️Alcohol exposure carries no known safe level in pregnancy and can cause fetal alcohol spectrum disorders, neurodevelopmental impairment, and growth restriction. Provide brief intervention, referral to substance-use treatment, and close multidisciplinary follow-up.

(Age 24 and BP 108/70 mm Hg are not high-risk on their own in pregnancy; “unsafe sexual practices” weren’t identified in this history.)


Distractor Analysis :

Rationale for Incorrect Options to be Available Soon

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