End
1 :

Blood pressure 142/84 mm Hg

Temperature 38.5° C (101.3° F)

Respiratory rate 24/min

Heart rate 99/min

Pain rating of 7 on a scale of 0 to 10

SpO2 96% on room air

Admitting Diagnosis: Appendicitis; scheduled for appendectomy Severe penicillin allergy

Hypertension

Gout

Rebound tenderness in the lower right quadrant of the abdomen

Tophi on fingers

Nausea and vomiting

Amylase 80 units/L (60 to 120 units/L)

WBC count 13,000/mm³ (5,000 to 10,000/mm³)

Platelets 200,000/mm³ (150,000 to 400,000/mm³)

Provider's Prescriptions

Furosemide 40 mg PO twice daily

Lisinopril 20 mg PO daily

Allopurinol 200 mg PO three times daily


A nurse is caring for a client who has a new prescription for cefazolin. Which of the following findings should the nurse identify as a contraindication to the administration of cefazolin? Select all that apply.


Answer Options

Hint : ⚠️Penicillin anaphylaxis → avoid cefazolin.

Correct Answers:

  • Allergy history


Rationale :

🚫A severe penicillin allergy is a contraindication to administering cefazolin, a first-generation cephalosporin, because of potential cross-reactivity within the β-lactam class.

🚫When the history suggests IgE-mediated reactions (e.g., anaphylaxis, angioedema, bronchospasm, immediate urticaria), the risk of a serious repeat reaction is clinically unacceptable.

🚫Before giving any β-lactam, the nurse should clarify the allergy details, verify reaction type and timing, and notify the provider to select a non-β-lactam alternative for perioperative prophylaxis if the allergy is severe.

🚫Medication safety requires checking the MAR/allergy band and reconciling allergies with new orders—especially for antibiotics—prior to first dose.

🚫Documenting the reaction and communicating it to the surgical and anesthesia teams helps prevent perioperative anaphylaxis and supports safe antibiotic stewardship.


Distractor Analysis :

Rationale for Incorrect Options to be Available Soon

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