End
1 :

Hint : ❀️Think anti-inflammatory.

Correct Answers:

  • Indomethacin
  • Colchicine


Rationale :

Indomethacin

🟣NSAIDs like indomethacin are first-line for pericarditis because they reduce inflammation and chest pain.

🟣They inhibit prostaglandin synthesis, decreasing the pericardial inflammatory response.

🟣Relief of pleuritic chest pain is one of the primary goals of treatment.

🟣NSAIDs also help prevent further pericardial effusion development.

🟣Monitoring includes GI side effects and renal function.

Colchicine

🟣Colchicine reduces recurrence of pericarditis and is often used with NSAIDs.

🟣It works by interfering with leukocyte activity and decreasing inflammatory response.

🟣Clinical guidelines recommend it for both acute and recurrent pericarditis.

🟣It improves outcomes and reduces the risk of chronic constrictive pericarditis.

🟣Side effects may include GI upset, so patient education is important.


Distractor Analysis :

Rationale for Incorrect Options to be Available Soon

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