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1 :

Hint : 🌙 Pineal hormone for sleep.

Correct Answers:

  • Melatonin


Rationale :

📌Melatonin, released by the pineal gland, is the key circadian regulator that aligns the sleep–wake cycle with environmental light–dark cues.

📌Darkness stimulates melatonin secretion, promoting sleep onset and continuity, while light suppresses secretion to support wakefulness.

📌The hormone acts on suprachiasmatic nucleus (SCN) pathways, synchronizing body temperature, hormone release, and alertness with night-time rest.

📌Blue-light exposure in the evening blunts melatonin, delaying sleep latency and shifting circadian phase.

📌Clinical uses include jet lag and shift-work disorder, where timed melatonin helps phase adjustment.


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